A listing of jodi-skiles medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
We want to learn more about the long-term effects of Hematopoietic Stem Cell Transplantation (HSCT) on the brain and blood vessels of patients with sickle cell disease. We want to understand: how the brain looks on scans, how it functions and what brain complications develop with BMT for sickle cell …
The primary purpose of the Research Sample Repository is to make blood samples available forh studies related to histocompatibility and hematopoietic cell transplantation (HCT)her cellular therapy. Representatives of participating centers and investigators or research groups may requesth samples contained in the Research Sample Repository for the purpose ofducting research including: …
This study aims to enroll 58 pre-adolescent (<13 years) pediatric participants with sickledisease (SCD) who have a pre-adolescent sibling bone marrow donor. All participants will go through a pre-transplant evaluation to find out if there are health problems that will keep them from being able to receive the transplant. It …
Patients with relapsed or refractory leukemia or lymphoma are often refractory to furtherhemotherapy. In this study, the investigators will attempt to use T cells obtained directlyhe patient, which can be genetically engineered to express a chimeric antigen receptor (CAR). The CAR used in this study can recognize CD22, a protein …
To determine the recommended phase 2 dose (RP2D) of vorinostat in children, adolescents and young adults following allogeneic HCT. Eligibility:A prospective patient for allogeneic BMT for malignant hematologic conditions Ages 3-30 Diagnoses include:Acute Leukemia in remissionChronic Myeologenous Leukemia (CML) Myelodysplastic syndrome (MDS) Additonal criteria must be met based on determination …
The purpose of this Managed Access Program (MAP) Treatment Plan is to provide access to CTL019, for acute lymphoblastic leukemia (ALL) or diffuse large b-cell lymphoma (DLBCL) patients with out of specification leukapheresis product and/or manufactured tisagenlecleucel out of specification for commercial release where no overwhelming safety concerns has been …
This study will evaluate the use of non- TBI (total body irradiation) conditioning for B-ALL patients with low risk of relapse as defined by absence of NGS-MRD (next generation sequencing minimal residual disease) before receiving a hematopoietic cell transplant (HCT).