Global AKI Study
K
Kavish Patidar
Primary Investigator
Enrolling By Invitation
18-100 years
All
Phase
N/A
100 participants needed
1 Location
Overview
The purpose of this study is to describe the clinical impact of acute kidney injury in people who have liver disease.
Description
Participants will first read and sign an Informed Consent and HIPAA Authorization form. Some health information about the participant, such as about his or her general health, medical treatments and care received while in hospital will be collected for the length of the hospital stay. While in the hospital, participation in this study will not require more time other than for the first visit when this study is explained; all of the data collected will be from a review of medical records.
About 90 days after you are discharged from the hospital, researchers may call participants to collect some additional information about their health and whether or not they have received a liver and/or kidney transplant.
Researchers will ask participants with acute kidney injury if they can collect about 5mL (about 1 teaspoon) of urine within the first 72 hours of your hospital admission.
Eligibility
You may be eligible for this study if you meet the following criteria:
-
Conditions:
Cirrhosis, acute kidney injury
-
Age: Between 18 Years - 100 Years
-
Gender: All
Inclusion Criteria:
- Patients with cirrhosis admitted to hospital for the treatment of a complication of liver disease (ascites, gastrointestinal bleeding, hepatic encephalopathy, bacterial infection, jaundice, etc).
Exclusion Criteria:
- Pregnancy
- Hepatocellular carcinoma outside Milan criteria (i.e., a single lesion <5 cm or multiple lesions [maximum of three], the largest of which measures ≤ 3 cm)
- Extrahepatic malignancy other than non-melanoma skin cancer within last 5 years
- Previously known severe extrahepatic disease (e.g., chronic renal failure requiring hemodialysis, severe congestive heart disease [NYHA class ≥ 3]; severe chronic obstructive pulmonary disease [GOLD class ≥ 3], psychiatric disorders)
- Previous solid organ transplantation
- HIV infection with CD4 count ≤ 250/mm3
- Patients who cannot provide prior informed consent and no legal surrogate decision maker.
Updated on
15 May 2024.
Study ID: 12275, GI-IIR-GLOBAL-AKI-STUDY
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