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Found 742 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Pelvic Health Electrically Evoked Recording (PEER) 2 Study (PEER 2)

C
Charles Powell, MD
18 years and older
All genders
Interventional
To collect physiological signals at several timepoints during the therapy evaluation period.
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Patient Satisfaction of Virtual vs In-Person Workup and Treatment of Lower Urinary Tract Symptoms.

M
Marcelino Rivera
18 years and older
Healthy Volunteer
All genders
This study is being done to compare usefulness of data collected in uroflowmetry, a test thatures the amount of urine released from the body, at home versus in the doctor's office. Additionally, investigators are assessing patient satisfaction when completing a virtual visit for lower urinary tract symptoms (LUTS), related to …
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ONC201 in H3 K27M-mutant Diffuse Glioma Following Radiotherapy (the ACTION Study) (ACTION)

All genders
Phase 3
Interventional
This is a randomized, double-blind, placebo-controlled, parallel-group, international, Phase 3 study in patients with newly diagnosed H3 K27M-mutant diffuse glioma to assess whetherwith ONC201 following frontline radiotherapy will extend overall survival andgression-free survival in this population. Eligible participants will have histologically diagnosed H3 K27M-mutant diffuse glioma and have completed standard …
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A Study of Combination Therapy With Guselkumab and Golimumab in Participants With Moderately to Severely Active Ulcerative Colitis (DUET-UC)

S
Sashidhar Sagi, MD
18-65 years
All genders
Phase 2
Interventional
The purpose of this study is to evaluate the efficacy and safety of JNJ-78934804 as comparedguselkumab and golimumab in participants with moderately to severely active ulcerativewho have had an inadequate initial response, loss of response, or intolerance to oneved advanced therapy.
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Phase 2b Study of GSK4532990 in Adults With NASH (HORIZON)

N
Niharika Samala, MD
18-75 years
All genders
Phase 2
Interventional
The purpose of this study is to measure improvements in liver fibrosis and inflammation with GSK4532990 compared with placebo in participants with NASH and advanced (F3) fibrosis. Theudy duration will be up to 76 weeks including the screening period. The treatment duration will be up to 52 weeks.
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Biologic Abatement and Capturing Kids' Outcomes and Flare Frequency in Juvenile Spondyloarthritis (BACK-OFF JSpA)

S
Stacey Tarvin, MD
8-21 years
All genders
Interventional
This randomized pragmatic trial will generate knowledge about strategies used to de-escalateumor necrosis factor inhibitor (TNFi) therapy in patients with juvenile spondyloarthritis with sustained inactive disease and are treated at one of the 29 participating pediatric healthcare systems. This open label study will be conducted in the setting of routined …
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APOLLO: A Randomized Phase II Double-Blind Study of Olaparib Versus Placebo Following Curative Intent Therapy in Patients With Resected Pancreatic Cancer and a Pathogenic BRCA1, BRCA2 or PALB2 Mutation

A
Anita Turk, MD
18 years and older
All genders
Phase 2
Interventional
This phase II trial investigates how well the addition of olaparib following completion ofurgery and chemotherapy works in treating patients with pancreatic cancer that has beenurgically removed (resected) and has a pathogenic mutation in BRCA1, BRCA2, or PALB2.b is an inhibitor of PARP, an enzyme that helps repair deoxyribonucleic acid …
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Safety and efficacy of a suction cervical stabilizer compared to the standard tenaculum for intrauterine procedures in the clinic setting.

A
Alissa Conklin
18-100 years
Female
Observational
What is the purpose of this study?To evaluate patient-reported pain, bleeding, and device efficiency along with provider satisfaction and ease of use between intrauterine procedures employing a suction cervical stabilizer (new device, FDA approved, atraumatic) or single-tooth tenaculum (standard, traumatic).  This device, cleared by the FDA in 2023, was studied …
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ROCK-D

K
Kenneth Lim
18-100 years
All genders
The purpose of the study is to identify the best diagnostic test that could be used to assess cardiovascular risk in patients on dialysis. The study will also develop a new scoring system that can more accurately calculate the risk of developing an adverse cardiovascular event.
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Human Tissue Sampling for Generation of Stem Cells

R
Rick Nelson, MD
12-95 years
All genders
The study of genetic hearing loss has been limited to animal models due to the difficulty accessing human tissue within the inner ear. We can now generate all of the components of the human inner ear in a culture dish using human stem cells from patients with known genetic type …
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