Health Research
and Clinical Studies

All IN for Health provides a list of hundreds of active health studies happening right here in Indiana. These health studies are conducted by faculty at Indiana University, Purdue University, and the University of Notre Dame.

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All IN for Health provides a list of hundreds of active health studies happening right here in Indiana. These health studies are conducted by faculty at Indiana University, Purdue University, and the University of Notre Dame.

Learn more

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Browse by Featured categories

Aging
Children, Families & Pregnancy
Dental
Online
Alcohol, Tobacco, or Other Substance Use
Alzheimer’s Disease & Dementia
Asthma,Lungs & Allergies
Bones, Muscles and Joints
Brain, Spine & Nervous System
Covid-19 & Infectious Disease
Diabetes, Heart and Blood Vessels
Digestive System (GI), Bowel & Liver
Health Mental, Behavioral Health & Developmental Conditions
Healthy Volunteer
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I H

IN Health

W S

Will Simon

S B

Sandeep Batra, MD

C L

Craig Lammert, MD

J M

Jessica MacLean

R W

Regina Weber

K B

Kevin Bell

J M

Jean Molleston, MD

B X

Bryan Xin

G D

Greg Durm, MD

J S

Jodi Skiles

Recently added/updated trials

Are you or someone you love receiving treatment for opioid addiction?

Are you or someone you love receiving treatment for opioid addiction?

R
R Andrew Chambers, MD
18 years - 65 years
All genders
Phase 1
Interventional
Are you interested in being opioid-free? Join our study!Researchers at Indiana University School of Medicine are looking for volunteers to take part in a study to test an investigational drug called Tezampanel for opioid withdrawal. The term “investigational drug” means it is not approved by the Food and Drug Administration (FDA). Participants must be willing to attend 3 outpatient visits and a 7-day inpatient stay at University Hospital in Indianapolis, IN.  Compensation will be provided. LEARN MORE BY CLICKING ON THE VIDEO BELOW:This study is looking at: 1) the safety of giving Tezampanel (TZP) to people,2) how TZP is broken down by the body,3) whether there is a difference in opioid withdrawal symptoms between people who receive TZP versus people who do not,4) whether people complete the 7-day inpatient stay and5) whether people get the injection of the opioid antagonist called, Vivitrol®. Who can take part?Individuals ages 18 - 65 with a diagnosis of opioid use disorder who are participating in outpatient services that provide medication treatments. Participants will be referred by their treating addiction provider.  
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A Phase 2 Double-Blind Placebo-Controlled Single-Dose Study of Pharmacodynamics, Pharmacokinetics, Safety, and Tolerability of REGN7544, an NPR1 Antagonist Monoclonal Antibody, in Patients With Postural Orthostatic Tachycardia Syndrome

A
Alex Barboi
18 years - 55 years
All genders
Phase 2
Interventional
What is the purpose of this study?This study is researching an experimental drug called REGN7544 (called "study drug"). The study is focused on participants with POTS.The aim of the study is to see how safe, tolerable, and effective the study drug is.The study is looking at several other research questions, including:How the study drug changes heart rate and blood pressure in participants with POTSWhat side effects may happen from taking the study drugHow much study drug is in the blood at different timesWhether the body makes antibodies against the study drug (which could make the study drug less effective or could lead to side effects)THIS STUDY IS ENROLLING BY INVITATION ONLY
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Point-of-Care Diagnosis and Management of Trauma Patients by Acoustic Tweezing Coagulometry

N
Nathan Alves
10 years - 100 years
All genders
Observational
What is the purpose of this study?The overall goal of the funded proposal is to develop prototypes of a portable and deployable point-of-care comprehensive coagulation analyzer for diagnosis and management of coagulation abnormalities in trauma patients.  The goal for the IU subaward is preliminary testing of the Levisonics’ coagulation device prototypes in trauma subjects at Methodist Hospital compared to standard of care clinical coagulation testing.  THIS STUDY IS ENROLLING BY INVITATION ONLY - Potential participants will be identified from the ED tracking board in Cerner or by a designated trauma group in Diagnotes and recruited from the Methodist emergency department. 
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An Interventional Efficacy and Safety Phase 3 Double-blind 2-arm Study to Investigate IV Followed by Oral Fosmanogepix Compared With IV Caspofungin Followed by Oral Fluconazole in Adult Participants With Candidemia and/or Invasive Candidiasis

N
Nicolas Barros, MD
18 years - 100 years
All genders
Phase 3
Interventional
What is the purpose of this study?The purpose of this clinical trial is to learn about the safety and effects of the study medicine (called Fosmanogepix) for the potential treatment of candidemia and/or invasive candidiasis, a life-threatening fungal infection caused by several species of yeast called Candida.The study is seeking patients who have a diagnosis of candidemia and/or invasive candidiasis.THIS STUDY IS ENROLLING BY INVITATION ONLY
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The natural history of C. trachomatis urethral infections in men who have sex with women

S
Stephen Jordan
18 years - 100 years
Accepts healthy volunteer
Male
What is the purpose of this study?Chlamydia is the most common bacterial sexually transmitted infection (STI) in the United States and is caused by the bacteria Chlamydia trachomatis, or “CT” for short. CT infects both men and women. The purpose of this study is to understand what causes some men to resist CT infection, spontaneously clear CT, and some to resist antibiotic cure so we can design a vaccine and lower CT rates in both men and women. We will compare samples that we collect from men who are being treated for Chlamydia to healthy samples to further study sexually-transmitted co-infections and the immune system.Who can take part?We are currently looking for healthy adult males (ages 18 and older) to participate.
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Dependency Processing in a Second Language

L
Laurent Dekydtspotter
18 years - 100 years
Accepts healthy volunteer
All genders
The purpose of this study is to understand how non-native speakers of English process grammar in the brain compared to native speakers of English.
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Observation or Radiation Therapy in Treating Patients With Newly Diagnosed Grade II Meningioma That Has Been Completely Removed by Surgery

18 years or above
All genders
Phase 3
Interventional
This randomized phase III trial studies how well radiation therapy works compared with observation in treating patients with newly diagnosed grade II meningioma that has been completely removed by surgery. Radiation therapy uses high energy x-rays to kill tumor cells and shrink tumors.
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