Neural Response to Risky Decision Making in Youth at High Risk for Substance Use Disorders and HIV

L
Leslie Hulvershorn, MD, MSc

Primary Investigator

Neural Response to Risky Decision Making in Youth at High Risk for Substance Use Disorders and HIV

Overview

The purpose of this study is to understand more about what leads some children to develop drug addiction as they grow older.

Description

The purpose of this study is to understand more about what leads some children to make potentially dangerous, risky decisions as they grow older.  We want to carefully study their behavior and scan their brains in a brain scanner (magnetic resonance imager or MRI). We will compare the children at risk with a group of typically developing children to understand more about the brain’s basis for making risky decisions. 

Eligibility

You may be eligible for this study if you meet the following criteria:

  • Conditions:
    Attention Deficit Hyperactivity Disorder,Conduct Disorder,Oppositional Defiance Disorder,Healthy,Substance Use Disorder,ODD,ADHD
  • Age: Between 11 Years - 12 Years
  • Gender: All

Inclusion Criteria
ADHD + ODD or CD diagnoses
Healthy
Right Handed
Exclusion Criteria
Family history of SUDs in 1st or 2nd degree relatives
Lifetime history of bipolar disorder, psychotic symptoms, pervasive development disorders or SUDs
Current major depressive disorder
Current psychopharmacologic treatment other than psychostimulants
History of neurological problems
Active or debilitating medical conditions
Active maternal substance use disorder during pregnancy
Claustrophobia
Pregnant
MRI contraindications
Left Handed
Additional Information:
Seeking children 11-12 years old with or without:
   - ADHD
   - Behavioral Issues
   - With or without paternal substance use
   

Participants will be paid for their participation.

Updated on 26 Oct 2023. Study ID: 1603169831

Interested in the study?

Select a study center that’s convenient for you, and get in touch with the study team.

Contact a study center