A Multicenter Randomized Double-Blinded Placebo-Controlled Trial to Evaluate the Safety and Efficacy of Inhaled Treprostinil in Subjects with Pulmonary Hypertension due to Parenchymal Lung Disease

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: lung disease | pulmonary hypertension
  • Age: Between 18 - 79 Years
  • Gender: Male or Female

Inclusion Criteria
Females of reproductive potential must be non-pregnant and non-lactating
Confirmed diagnosis of World Health Organization Group 3 PH associated with idiopathic interstitial pneumonia or chronic hypersensitivity pneumonitis
Exclusion Criteria
Has a diagnosis of pulmonary arterial hypertension or PH for reasons other than ILD
Has shown intolerance or significant lack of efficacy to a prostacyclin or prostacyclin analogue that resulted in discontinuation or inability to effectively titrate that therapy
Has received any prostacyclin therapy within 30 days of informed consent, except for acute vasoreactivity testing
Has evidence of clinically significant left-sided heart disease
Use of any inhaled tobacco products or significant history of drug abuse within six months prior to first dose of study drug
Exacerbation of underlying lung disease or active pulmonary or upper respiratory infection within 30 days of the first dose of study drug
Initiation of pulmonary rehabilitation within 12 weeks prior to the first dose of study drug
Has uncontrolled systemic hypertension
Has any form of congenital heart disease or congenital hear defect
Has anemia
Has any musculoskeletal disorder, is using a device to assist walking, or has any other condition that would limit ambulation
Use of any investigational drug/device, or participation in any investigational study within 30 days prior to the first dose of study drug

Recruitment Status

Open

Contact the research team to learn more about this study.

Fields marked with asterisk (*) are required

Please verify that you are not a bot.

By clicking "Contact Research Team", your contact information will be sent securely to the research staff associated with the study. You will also receive a copy of this email in your inbox, as well as other notifications to determine your participation status in the study.

Volunteer Sign up

Volunteer Registry

Create your profile and be matched to research opportunities

Register Now!

If you need assistance finding a study or if you have any questions, please email: ctsirro@iu.edu or call us at (317) 278-2176