Phase I trial of azacitidine plus nivolumab following reduced-intensity allogeneic PBSC transplantation for patients with AML and high-risk myelodysplasia

Study Overview

The purpose of this study is to find the maximum safe dose of nivolumab alone, and of nivolumab combined with azacitidine after reduced-intensity allogeneic peripheral blood stem cell (PBSC) transplantation. Another purpose is to see how the study drugs affect different aspects of transplant such as infection and disease response.

  • IRB Number: 1905948967 (BTCRC-AML18-342)
  • Research Study Identifier: TX10509
  • Principal Investigator: Sherif Farag, MD

Recruitment Status


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