Role of Aging in GCN2-dependent wound healing

D
Dan Spandau

Primary Investigator

Role of Aging in GCN2-dependent wound healing

Overview

When a normal healthy adult's skin is wounded, their skin usually heals without difficulty; however, if a person damages their skin while they are sick or if they have a chronic disease, the wound may not heal as quickly. Also, as we age, the wound healing process is slowed and delayed. The purpose of this study is to examine acute wound healing to determine whether a specific mechanism in how we respond to stress plays a role in the aging-related decline in wound healing. It will determine whether defects in this stress response occur with age and if it suppresses wound healing.

Description

Reccruiting Veterans Only

Eligibility

You may be eligible for this study if you meet the following criteria:

  • Conditions:
    healthy
  • Age: Between 20 Years - 100 Years
  • Gender: All

Inclusion Criteria
1.Age: either between 20-28 years old or at least 65 years old
2.Good general health
 
Exclusion Criteria
1. Diagnosis of diabetes mellitus
2. History of abnormal scarring
3. History of immunosuppression
4. History of abnormal skin infections
5. Allergies to xylocaine anesthetic
6. History of bleeding disorders
7. Use of anticoagulants
8. Unable to understand informed consent document
Additional Information:

Updated on 09 Mar 2024. Study ID: 1909990266

Connect with a study center near you

What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

You are contacting

Investigator Avatar

Primary Contact

site

Interested in the study?

Select a study center that’s convenient for you, and get in touch with the study team.

Contact a study center