Zoster Eye Disease Study (ZEDS): A multicenter, randomized trial of valacyclovir in patients with Herpes Zoster Ophthalmicus (HZO)

Study Overview

To evaluate whether or not prolonged suppressive oral antiviral treatment with valacyclovir reduces complications of HZO including new or worsening dendriform epithelial keratitis, stromal keratitis, endothelial keratitis, and/or iritis and/or postherpetic neuralgia compared to placebo.

Study Description

Study location can be either the Glick Eye Institute on the IUPUI campus, or at the Glick Eye Institute Springmill, which is located on N. Illinois St.


  • IRB Number: 1903188647
  • Research Study Identifier: TX10599
  • Principal Investigator: Shaohui Liu, MD

Recruitment Status

Open

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