A Phase 1 Study to Evaluate the Safety and Tolerability of a Study Drug in Subjects with Early Alzheimer's Disease (AD)

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: alzheimers disease | MCI | alzheimer's | early alzheimer's disease | alzheimers | Alzheimer's disease
  • Age: Between 55 - 85 Years
  • Gender: Male or Female
Inclusion Criteria
Diagnosis of amnestic MCI or probable mild AD
A minimum of 6 years of education of a good work history
Study partner who has frequent contact with the subject, and can accompany the subject to most visits to answer questions about the subject
Adequate visual and hearing ability
Good general health with no disease expected to interfere with the study
Must speak English fluently

Female participants must be post-menopausal for at least 2 consecutive years or surgically sterile (bilateral tubal ligation, hysterectomy or bilateral oophorectomy) for at least 6 months prior to screening
Female participants will be given a urine pregnancy test at the screening visit for which they should test negative

Exclusion Criteria
History of psychiatric disorder such as schizophrenia, bipolar disorder or major depression
Other neurodegenerative diseases, including Parkinson's disease and Huntington's disease, or cerebral tumor
Dementia other than AD, such as Acquired Immunodeficiency Syndrome (AIDS), Creutzfeldt-Jakob disease (CJD), Lewy Bodies dementia (LBD), Cerebrovascular dementia (CVD), Progressive Supranuclear Palsy (PSP), or normal pressure hydrocephalus (NPH)
History of seizures
Current serious or unstable illness including cardiovascular, hepatic, renal, gastroenterologic, respiratory, endocrinologic, neurologic, psychiatric, immunologic, or hematologic disease or other conditions
Cancer or has had a malignant tumor within the past 3 years, except patients who underwent potentially curative therapy with no evidence of recurrence
Participation in another investigational clinical trial within 16 weeks prior to screening
Resides in a skilled nursing facility
History of lumbar spine surgery or chronic back pain (CLBP)

Recruitment Status

Open

Check to see if you pre-qualify for the study.

Are you between the ages of 55 and 85? (inclusive)

If you are filling this out for a loved one, please answer based on their information.

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