Dopamine and Smoking Behaviors

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: healthy | smoking | smokers
  • Age: Between 18 - 55 Years
  • Gender: Male or Female
Inclusion Criteria
Able to complete and understand study questionnaires and procedures in English
Otherwise healthy male and female cigarette smokers
Right-handed
Subjects should be daily smokers (not "chippers")
 
Exclusion Criteria
Any neurological or other medical disorder which may compromise subject safety or influence study outcomes as determined by the PI
Presenting to the laboratory with a positive BrAC on the screening visit
Women who are pregnant, breast-feeding, or of childbearing potential and not using birth control
Taking any medication in the past 30 days which could influence study outcomes
Taking prescription opioid medication
Testing positive for amphetamine, cocaine, opiates, benzodiazepines, or barbiturates determined by urine toxicology screening
A history of seizures
Having no telephone or a reliable way in which study personal can contact them
Subjects who are claustrophobic and cannot tolerate imaging procedures
Subject who are contraindicated for magnetic resonance imaging (MRI) on standard IU screening forms: subjects who have metal implants, surgical devices, or other metal objects that would compromise the subject's health during the MRI
Subjects who weigh > 350 lb
Refusal or inability to refrain from smoking the day of the PET imaging study
Any reason that, in the opinion of the investigators, may put the subject at risk or that may compromise the validity or generalizability of the data

Recruitment Status

Open

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