HOW HEALTHY IS YOUR AIRWAY? Join our study to see if a molecule in the airway, called GSNO, is helping or hurting asthma.
J
James Chmiel
Primary Investigator
Overview
Airway environments can be different from
person to person - for example some airways have more of the molecule GSNO (a
type of small particle that protects people's airways and is naturally produced
by the body) than others. The level of GSNO in the airway can impact a person’s
asthma. Researchers at Indiana University School of Medicine are researching
how to identify the level of GSNO in an airway and if adding GSNO to the airway
could impact a person’s asthma. In this study, researchers will:
·
Look at your
specific airway’s environment and evaluate the severity of your asthma
·
Collect some airway
samples and measurements to compare to other levels of asthma
·
Measure if your
airway responds to a breathed-in treatment of GSNO
Description
Who is Eligible
This study is for people 18-50 years of age with asthma who also:
- Have had no recent flares
- Have had no recent change in medication
- Are available for 3-4 clinic visits over 2-12 weeks
-Are not a current smoker
What is Involved
·
Study participation
involves 3-4 study visits at Riley Hospital in Indianapolis, IN over the course
of 2-12 weeks.
Study visits will include:
·
Measurements of
airway function and inflammation
·
A research
bronchoscopy, which is a procedure that uses a scope to look inside the lungs
·
A breathed-in
treatment of GSNO
Compensation
·
Participants will be
compensated for their time and could receive up to $500 for completing all
study requirements
Eligibility
You may be eligible for this study if you meet the following criteria:
-
Conditions:
asthma,healthy
-
Age: Between 18 Years - 50 Years
-
Gender: All
How to Participate
IF YOU ARE INTERESTED IN PARTICIPATING IN
THIS STUDY please complete the pre-screener questions below to see if you
qualify.
You may also contact the study team
directly at 317-274-8895 or email myasthma@iupui.edu
Additional information
Full study title – Methods to
Identify and Treat Severe Asthma Patients, Project 1: GSNOR Phenotyping and
GSNO Challenge
Updated on
24 Apr 2024.
Study ID: 1904630156