HOW HEALTHY IS YOUR AIRWAY? Join our study to see if a molecule in the airway, called GSNO, is helping or hurting asthma.

J
James Chmiel

Primary Investigator

HOW HEALTHY IS  YOUR AIRWAY? Join our study to see if a molecule in the airway, called GSNO, is helping or hurting asthma.

Overview

Airway environments can be different from person to person - for example some airways have more of the molecule GSNO (a type of small particle that protects people's airways and is naturally produced by the body) than others. The level of GSNO in the airway can impact a person’s asthma. Researchers at Indiana University School of Medicine are researching how to identify the level of GSNO in an airway and if adding GSNO to the airway could impact a person’s asthma. In this study, researchers will: 
·         Look at your specific airway’s environment and evaluate the severity of your asthma
·         Collect some airway samples and measurements to compare to other levels of asthma
·         Measure if your airway responds to a breathed-in treatment of GSNO

Description

Who is Eligible
This study is for people 18-50 years of age with asthma who also:
- Have had no recent flares
- Have had no recent change in medication
- Are available for 3-4 clinic visits over 2-12 weeks
-Are not a current smoker
What is Involved
·         Study participation involves 3-4 study visits at Riley Hospital in Indianapolis, IN over the course of 2-12 weeks.
 
Study visits will include:
 
·         Measurements of airway function and inflammation
·         A research bronchoscopy, which is a procedure that uses a scope to look inside the lungs
·         A breathed-in treatment of GSNO
 
Compensation
·         Participants will be compensated for their time and could receive up to $500 for completing all study requirements

Eligibility

You may be eligible for this study if you meet the following criteria:

  • Conditions:
    asthma,healthy
  • Age: Between 18 Years - 50 Years
  • Gender: All

How to Participate
IF YOU ARE INTERESTED IN PARTICIPATING IN THIS STUDY please complete the pre-screener questions below to see if you qualify.
 
You may also contact the study team directly at 317-274-8895 or email myasthma@iupui.edu
 

Additional information
Full study title – Methods to Identify and Treat Severe Asthma Patients, Project 1: GSNOR Phenotyping and GSNO Challenge 

Updated on 02 Jan 2024. Study ID: 1904630156

Interested in the study?

Select a study center that’s convenient for you, and get in touch with the study team.

Contact a study center