Quantifying Endothelial Dysfunction and Inflammatory Changes in Low-Risk Chest Pain Patients with Associated Anxiety Identified in the ED: A Recruitment Pilot Study

Study Overview

SUBJECTS ARE BEING ENROLLED THROUGH THE EMERGENCY DEPARTMENT (ER) BY INVITATION ONLY

The purpose of this study is to learn about patients that present to the Emergency Department with low risk chest pain associated with anxiety or depression. We hope to study how patients’ endothelium (the cells that line blood vessels) function under different conditions.

We also hope to study how anxiety and/or depression affect markers of inflammation found in the blood.

Additionally, we hope to learn more about the obstacles that potentially prevent subjects from attending follow up appointments.

 

 

Study Description

In the emergency department, subjects will complete questionnaires, an audio-recorded interview, and a blood draw. 

Subjects will then be asked to complete a follow-up visit at the Clinical Research Center at IU Health University Hospital.  During the follow-up visit, subjects will do the following:

  • Have their blood drawn
  • An ultrasound with nitroglycerin
  • Complete questionnaires along with a brief interview.

Participation in this study will last approximately one month and subjects will be compensated for their time.


  • IRB Number: 1910739594
  • Research Study Identifier: TX11182
  • Principal Investigator: Paul Musey, MD

Recruitment Status

Enrolling By Invitation

If you need help finding a study or have any questions, please contact us at inhealth@iu.edu or by phone at (888) 264-0005.

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If you need help finding a study or have any questions, please contact us at inhealth@iu.edu or by phone at (888) 264-0005.