Functional and Neurochemical Substrates of Chemotherapy-Related Cognitive Deficits

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: chemobrain | breast cancer | chemotherapy-related cognitive deficits
  • Age: Between 18 - 55 Years
  • Gender: Female
Inclusion Criteria
Able to complete and understand study questionnaires and procedures in English
Breast cancer survivors with a history of non-metastatic disease and chemotherapy treatment, between 6 months to five years post-chemotherapy completion
OR
Healthy
Exclusion Criteria
Any neurological or other medical disorder which may compromise subject safety or influence study outcomes (e.g., stroke, Parkinson's Disease, epilepsy, high blood pressure, diabetes, liver disease, cardiovascular disease, metastatic brain cancer, dementia)
Women who are pregnant, breast-feeding, or of childbearing potential and not using birth control
Current cigarette or marijuana smoking
Taking any medication in the past 30 days which could influence study outcomes (e.g. dopaminergic psychotropic medications or SNRIs)
Taking prescription opioid medication
Dependence on any drug other than caffeine or nicotine
Having no telephone or a reliable way in which study personnel can contact them
Subjects who are claustrophobic and cannot tolerate imaging procedures
Subjects who are contraindicated for magnetic resonance imaging (MRI) on standard IU screening forms: subjects who have metal implants, surgical devices, or other metal objects that would compromise the subject?s health during the MRI
Subjects who weigh > 350 lb. (upper weight limit of scanner beds)

Recruitment Status

Open

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