STEPS to Enhance Physical Activity (STEPS) after Hematopoietic Stem Cell Transplantation (HCT) for Multiple Myeloma

E
Eileen Hacker

Primary Investigator

Overview

The purpose of this pilot study is to test the preliminary effects of a free-living physical activity intervention, STEPS to Enhance Physical Activity (STEPS), compared to usual care on fatigue (tiredness), functional ability (ability to perform tasks associated with daily living, like moving from a sitting to standing position), muscle strength, physical activity, and quality of life in people with multiple myeloma treated with autologous hematopoietic cell transplantation (HCT).

Description

This pilot study addresses the National Institutes of Health strategic plan to build symptom science through promotion of personalized health strategies in people with chronic and/or life-limiting illnesses. The purpose is to test the preliminary effects of a free-living physical activity intervention, STEPS to Enhance Physical Activity (STEPS), on fatigue, functional ability, muscle strength, physical activity, and quality of life in people with multiple myeloma (MM) treated with autologous hematopoietic stem cell transplantation (HCT).

Eligibility

You may be eligible for this study if you meet the following criteria:

  • Conditions:
    multiple myeloma
  • Age: Between 18 Years - 100 Years
  • Gender: All

Inclusion Criteria
Cognitively able to understand the purpose of the research
Undergoing HCT for treatment of multiple myeloma
To participate in the post-hospital phase of the intervention, subjects must be ambulatory and discharged to home.
Use of an assistive ambulation device, such as canes and walkers, is permitted.
Exclusion Criteria
Subjects who present with significant comorbidity that would make it potentially unsafe to participate in physical activity.
We will adhere to the American College of Sports Medicine guidelines and exclude those who do not meet their guidelines for exercise testing.
Evidence of restrictive lung disease or asthma, the presence of a potentially debilitating disease such as congestive heart failure, kidney disease, liver failure or cirrhosis, musculoskeletal or degenerative nerve disease, etc.
The presence of a condition that would make it potentially unsafe to participate in physical activity or functional ability tests, including a history of a recent myocardial infarction, unstable angina pectoris, uncontrolled cardiac arrhythmias causing symptoms or hemodynamic compromise, severe symptomatic aortic stenosis, uncontrolled symptomatic heart failure, and/or uncontrolled metabolic disease.
Cognitively unable to understand the purpose of the study.


Additional Information:

Updated on 09 Mar 2024. Study ID: 1712292634 (IUSCC-0653)

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