A Phase 1 First-in-Human Open-label Study Evaluating the Safety Tolerability Pharmacokinetics and Efficacy of AMG 510 in Subjects With Advanced Solid Tumors With a Specific KRAS Mutation.

Study Overview

This research study is being done to test the effects of a new investigational drug therapy called AMG 510 which is being investigated for the treatment of advanced solid tumors with a specific KRAS mutation.

Study Description

This is a Phase 1 first in human, open-label study evaluating the safety, tolerability, pharmacokinetics, and Efficacy, of AMG 510 in Subjects with Advanced Solid Tumors with a Specific KRAS Mutation.

Additional Information

Participants will be compensated for their participation.

  • IRB Number: 1806140760 (20170543)
  • Research Study Identifier: TX9005
  • Principal Investigator: Greg Durm, MD

Recruitment Status


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