PHO-COG-FALLON-ACNS0332; Efficacy of Carboplatin Administered Concomitantly With Radiation and Isotrectinoin as a Pro-Apoptotic Agent in Other Than Average Risk Medulloblastoma/PNET Patients

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: medulloblastoma | pineoblastoma
  • Age: Between 3 - 21 Years
  • Gender: Male or Female

Inclusion Criteria
Histologically confirmed diagnosis of medulloblastoma
Meets 1 of the following criteria: M0 medulloblastoma with > 1.5 cm^2 residual tumor, M+ medulloblastoma, M0 or M+ supratentorial PNET (including pineoblastoma), Diffusely anaplastic medulloblastoma with any M-stage or residual tumor
Must have undergone stereotactic biopsy or attempted neurosurgical resection of the tumor within the past 31 days
Karnofsky performance status (PS) 30-100% (for patients > 16 years of age) OR Lansky PS 30-100% (for patients ? 16 years of age)
Life expectancy > 8 weeks
Exclusion Criteria
pregnant or nursing

Recruitment Status


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