Dominantly Inherited Alzheimer Network (DIAN)
Are you eligible to participate in this study?
You may be eligible for this study if you meet the following criteria:
Age: Between 18 - 100 Years
Gender: Male or Female
Participant is cognitively normal or if demented does not require nursing home-level care.
Participant has identified two persons (minimum of one) who are not their full-blooded siblings who can serve as collateral sources for the study.
Participant is fluent in English at the 6th grade level or above
Pregnant women should not complete any in-person visit measures
Treatment with blood thinners, e.g. Warfarin
Lumbar spinal surgery within the last 6 months prior to screening, or any lumbar spinal surgery that interferes with anatomy of the inter-vertebral spaces.
History of chronic or repeat CSF leakage following previous LP(s)
Active infectious process
Current or recent participation in research studies involving radioactive agents
Electronically, magnetically, and mechanically activated implants
Metallic splinters in the eye
Ferromagnetic haemostatic clips in the central nervous system