PHASE 2 STUDY OF ADXS11-001 IN SUBJECTS WITH PERSISTENT/RECURRENT LOCO-REGIONAL OR METASTATIC SQUAMOUS CELL CARCINOMA OF THE ANORECTAL CANAL
Bert O'Neil, MD
Primary Investigator
Jessica MacLean
Primary Investigator
Overview
This is a 2-stage study. Stage 1 and 2 of the study are monotherapy evaluations of ADXS11-001 in 31 and 24 subjects, respectively with persistent/recurrent, loco-regional or metastatic anal cancer or HPV+ squamous cell carcinoma of the rectum that are either treatment na?ve in the metastatic setting or have progressed or become intolerant to platinum based therapy.
Description
This is a 2-stage study. Stage 1 and 2 of the study are monotherapy evaluations of ADXS11-001 in 31 and 24 subjects, respectively with persistent/recurrent, loco-regional or metastatic anal cancer or HPV+ squamous cell carcinoma of the rectum that are either treatment na?ve in the metastatic setting or have progressed or become intolerant to platinum based therapy.
Eligibility
You may be eligible for this study if you meet the following criteria:
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Conditions:
anal cancer,rectal cancer
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Age: Between 18 Years - 100 Years
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Gender: All
