Targeting Polyamines using DFMO in Persons with Type 1 Diabetes: A Randomized Double-Masked Placebo-Controlled Phase I/II Study to Evaluate the Safety Tolerability and Initial Pharmacodynamics of Multiple Ascending Doses

Study Overview

The purpose of this study is to determine if different doses of a drug known as DFMO have an effect on reducing the amount of stress that is experienced by the body's beta cells and preserves residual c-peptide.

Study Description

The purpose of this study is to determine if different doses of a drug known as DFMO have an effect on reducing the amount of stress that is experienced by the body's beta cells and preserves residual c-peptide.

Additional Information

Participants will be paid for their participation.


  • IRB Number: 1411735324
  • Research Study Identifier: TX4823
  • Principal Investigator: Linda DiMeglio, MD

Recruitment Status

Closed
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