Role of keratinocyte-derived cytokines in epidermal injury and atopic dermatitis

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: psoriasis | atopic dermatitis | healthy
  • Age: Between 21 - 100 Years
  • Gender: Male or Female
Inclusion Criteria
For subjects with atopic dermatitis, only patients with active atopic dermatitis will be enrolled
For subjects with psoriasis, only patients with active plaque psoriasis will be enrolled
Exclusion Criteria
Patients without active atopic dermatitis
Patients without active plaque psoriasis
No current or use within the past 6 months of any systemic immunosuppressants including systemic steroids, methotrexate, cyclosporine, azathioprine, mycophenolate mofetil, acitretin, isotretinoin, TNFalpha inhibitors and ustikenumab
No prior use of UVB- or UVA-based phototherapies or tanning beds within the past 3 months
No current or use within the past 1 week of topical steroids, topical calcineurin inhibitors or other toopical medications (other than bland emollients) on the skin sites that will be used for the proposed studies
No history of abnormal scarring
No history of allergy to lidocaine or other amide local anesthetics
No history of systemic immunosuppression or abnormal serious skin infections necessitating hospitalization
No history of bleeding disorders or use of anticoagulants

Recruitment Status

Open

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