Evaluation of the Fluoride Response of a Modified In situ Caries Model
Domenick Zero, DDS, MS
Primary Investigator
Jessica MacLean
Primary Investigator
Overview
The purpose of this study is to evaluate the fluoride dose response of different dentifrice fluoride concentrations - 0, 250, 500 and 1100 ppm fluoride of our existing in situ model involving the use of human enamel specimens placed in the buccal flange area of the subjects partial denture with the modified model involving placement of bovine enamel specimens in a denture tooth location.
Description
The purpose of this study is to evaluate the fluoride dose response of different dentifrice fluoride concentrations - 0, 250, 500 and 1100 ppm fluoride of our existing in situ model involving the use of human enamel specimens placed in the buccal flange area of the subjects partial denture with the modified model involving placement of bovine enamel specimens in a denture tooth location.
Eligibility
You may be eligible for this study if you meet the following criteria:
-
Conditions:
In situ Caries
-
Age: - 100 Years
-
Gender: All