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Phase 2 Study of Imatinib in Children with Neurofibromatosis and Airway Tumors

Study Overview

The purpose of this study is to look at a subset of plexiform neurofibromas and determine if the airway tumors are more sensitive to imatinib therapy.

Study Description

The purpose of this study is to determine if NF1 associated pediatric airway-related plexiform neurofibromas represent a subset of plexiform neurofibromas with an inherent sensitivity to imatinib therapy and if imatinib therapy will show efficacy by improving respiratory function as assessed by pulmonary function tests and sleep study evaluations as children with airway tumors.

Additional Information

Participants will be paid for their participation.


  • IRB Number: 1505569560
  • Research Study Identifier: TX5482
  • Principal Investigator: Kent Robertson, MD

Recruitment Status

Open

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