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Pathogenetic Basis of Aortopathy and Aortic Valve Disease

Study Overview

The purpose of this study is to identify genes related to aortopathy and aortic valve disease in order to determine the risk and severity of aortic disease in individuals starting at an early age or stage of disease.

Study Description

The purpose of this study is to obtain information from individuals and their families in order to define the complex genetic and pathogenic basis of thoracic aortic aneurysm and other forms of aortopathy and aortic valve disease by identifying new disease-causing genes and by identifying important genetic modifiers for aortic/aortic valve disease severity.

Additional Information

Participants may be compensated for their participation.


  • IRB Number: 1509977311
  • Research Study Identifier: TX5699
  • Principal Investigator: Benjamin Landis, MD

Recruitment Status

Open

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