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A Phase I First-in-Human Multicenter Randomized Double-Blinded Placebo- Controlled Study of the Safety and Efficacy of Allogeneic Mesenchymal Stem Cells in Cancer Survivors with Anthracycline-Induced Cardiomyopathy

Study Overview

The primary purpose of this study is to examine the safety and feasibility of delivering allogeneic human mesenchymal stem cells (allo-MSCs) by transendocardial injection to cancer survivors with left ventricular (LV) dysfunction secondary to anthracycline-induced cardiomyopathy (AIC).

Study Description

The purpose of this study is to determine the safety of allogeneic MSCs in patients with anthrcycline-induced cardiomyopathy.


  • IRB Number: 1510353290 (SURG-NHLBI-FINET-SENECA)
  • Research Study Identifier: TX5993
  • Principal Investigator: Michael Murphy, MD

Recruitment Status

Open

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