This research study is currently not recruiting patients.

A Study of the Effects of Experimental Rinse Formulations Ex Vivo in an In-Situ Biofilm Mode



Study Overview

Phase A: To determine if treatment ex vivo with an experimental rinse containing dextranase and mutanase decreases extracellular polysaccharide formation and the mass of biofilm on a bovine enamel specimen compared to the placebo rinse in a two week in-situ biofilm model. Phase B: To determine if treatment ex vivo with an experimental rinse containing dextranase and mutanase followed by an essential oils rinse versus an essential oils product alone decreases extracellular polysaccharide formation and the mass of biofilm on a bovine enamel specimen compared to the placebo rinse in a two week in-situ biofilm model.


Study Description

Phase A: To determine if treatment ex vivo with an experimental rinse containing dextranase and mutanase decreases extracellular polysaccharide formation and the mass of biofilm on a bovine enamel specimen compared to the placebo rinse in a two week in-situ biofilm model. Phase B: To determine if treatment ex vivo with an experimental rinse containing dextranase and mutanase followed by an essential oils rinse versus an essential oils product alone decreases extracellular polysaccharide formation and the mass of biofilm on a bovine enamel specimen compared to the placebo rinse in a two week in-situ biofilm model.

Research Study Identifier: TX9232
ClinicalTrials.gov Identifier: NCT1808800034
Principal Investigator: Domenick Zero, DDS, MS


Not Recruiting

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