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Risk-Stratified Randomized Phase III Testing of Blinatumomab (NSC#765986) in First Relapse of Childhood B-Lymphoblastic Leukemia (B-ALL)
This randomized phase III trial compares how well blinatumomab works compared with standard combination chemotherapy in treating patients with B-cell ...
Exact
Phase N/A
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A Phase III Randomized Trial for Newly Diagnosed High Risk B-Lymphoblastic Leukemia (B-ALL) Including a Stratum Evaluating Dasatinib (NSC#732517 ...
This randomized phase III trial is studying how well combination chemotherapy works in treating young patients with newly diagnosed acute ...
Exact
Phase N/A
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A Phase 2 Study of the JAK1/JAK2 Inhibitor Ruxolitinib With Chemotherapy in Children With De Novo High-Risk CRLF2-Rearranged and ...
The purpose of this study is to find the best dose of ruxolitinib to use with standard chemotherapy in children ...
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Phase N/A
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International Phase 3 Trial in Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia (Ph+ALL) Testing Imatinib in Combination With Two Different Cytotoxic ...
This randomized phase III trial studies how well imatinib mesylate and combination chemotherapy work in treating patients with newly diagnosed ...Exact
Phase N/A
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A Groupwide Pilot Study to Test the Tolerability and Biologic Activity of the Addition of Azacitidine (NSC# 102816) to Chemotherapy ...
This pilot phase II trial studies the side effects of azacitidine and combination chemotherapy in infants with acute lymphoblastic leukemia ...Exact
Phase N/A
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A Dose Escalation Study of Intensity Modulated Total Marrow Irradiation (IMRT-TMI) with Fludarabine as a Myeloablative Conditioning Regimen for Allogeneic ...
The purposes of this study are to: (1) find the most effective dose of a new type of radiation therapy ...Exact
Phase N/A
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An Open-label Multicenter Phase 2 Study Evaluating the Efficacy and Safety of Daratumumab in Pediatric and Young Adult Subjects > ...
The purpose of this study is to see if Daratumumab is useful for treating pediatric (subjects aged >=1 to ...Exact
Phase N/A
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Evaluation of an Exercise intervention for Vincristine induced peripheral neuropathy in pediatric cancer patients
The purpose of this study is to evaluate the feasibility and acceptability of exercise as an intervention for vincristine-induced peripheral ...
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Phase N/A
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A Randomized Web-based Physical Activity Intervention among Children and Adolescents with Acute Lymphoblastic Leukemia
This randomized clinical trial studies how well web-based physical activity intervention works in improving long term health in children and ...
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Phase N/A
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Managed Access Program (MAP) to Provide Access to CTL019, for ALL or DLBCL Patients With Out of Specification Leukapheresis Product ...
The purpose of this Managed Access Program (MAP) Treatment Plan is to provide access to CTL019, for acute lymphoblastic leukemia ...
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