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A Dose Escalation Study of Intensity Modulated Total Marrow Irradiation (IMRT-TMI) with Fludarabine as a Myeloablative Conditioning Regimen for Allogeneic ...
The purposes of this study are to: (1) find the most effective dose of a new type of radiation therapy ...Exact
Phase N/A
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Phase III Randomized Study of Crenolanib versus Midostaurin Administered Following Induction Chemotherapy and Consolidation Therapy in Newly Diagnosed Subjects with ...
This is a phase III randomized multi-center study designed to compare the efficacy of crenolanib with that of midostaurin when ...Exact
Phase N/A
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Risk-stratified Therapy for Acute Myeloid Leukemia in Down Syndrome
The purpose of this study is to treat for AML in Down Syndrome patients.
Exact
Phase N/A
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Phase I trial of azacitidine plus nivolumab following reduced-intensity allogeneic PBSC transplantation for patients with AML and high-risk myelodysplasia
The purpose of this study is to find the maximum safe dose of nivolumab alone, and of nivolumab combined with ...
Exact
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Clinical Transplant-Related Long-term Outcomes of Alternative Donor Allogeneic Transplantation (CTRLALT-D)
The primary objective is to estimate and compare overall survival between the two arms: patients who are Very Likely ...
Exact
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A PHASE II TRIAL OF EPIGENETIC PRIMING IN PATIENTS WITH NEWLY DIAGNOSED ACUTE MYELOID LEUKEMIA
The purpose of this study is to determine if epigenetic priming with DNA methyltransferase inhibitors (DMTi) prior to chemotherapy blocks ...
Exact
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A Randomized Phase II/III Study of Conventional Chemotherapy +/- Uproleselan (GMI-1271) in Older Adults with Acute Myeloid Leukemia Receiving Intensive ...
The purpose of this study is to see if we lower the chance of AML returning or getting worse by ...
Exact
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Phase I/II study augmenting TAK-659 action in relapsed/refractory AML by addition of the proteasome inhibitor Ixazomib Big Ten ...
The purpose of this study is to test the safety and efficacy of combining two drugs, ixazomib and TAK-659. It ...
Exact
Phase 
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BMT CTN 1703/1801: A Randomized, Multi-Center, Phase III Trial of Tacrolimus/ Methotrexate versus Post-Transplant Cyclophosphamide/Tacrolimus/Mycophenolate Mofetil in ...
The primary objective of the trial is to compare 1 year GVHD-free, relapse-free survival (GRFS) between the two GVHD prophylaxis ...
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