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Role of Microenvironmental-Derived AXII in Myeloma Bone Disease An Exploratory Model
The purpose of this research is to learn if substances that cause bone destruction are increased in multiple myeloma patient ...
Exact
Phase N/A
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A Path Analysis Modeling of the Interaction of AXII and/or AXIIR with the Changes in Cytokines and Myeloma Bone ...
The purpose of this research study is to learn if substances that cause bone destruction are increased in the blood ...
Exact
Phase N/A
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IUCRO-0498; Role of Osteocytes in Myeloma Bone Disease
The purpose of this study is to learn if substances that may cause bone destruction are increased in blood or ...
Exact
Phase N/A
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A Randomized Phase II Trial of Brentuximab Vedotin (SGN35 NSC# 749710) or Crizotinib (NSC#749005 Commercially Labeled) in Combination With ...
This partially randomized phase II trial studies how well brentuximab vedotin or crizotinib and combination chemotherapy works in treating patients ...
Exact
Phase N/A
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A Phase III Randomized Trial Investigating Bortezomib (NSC# 681239) on a Modified Augmented BFM (ABFM) Backbone in Newly Diagnosed T- ...
This randomized phase III clinical trial compares how well combination chemotherapy works when given with or without bortezomib in treating ...
Exact
Phase N/A
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Risk-Stratified Randomized Phase III Testing of Blinatumomab (NSC#765986) in First Relapse of Childhood B-Lymphoblastic Leukemia (B-ALL)
This randomized phase III trial compares how well blinatumomab works compared with standard combination chemotherapy in treating patients with B-cell ...
Exact
Phase N/A
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A Phase I/II Study of MK-3475 (Pembrolizumab) in Children with advanced melanoma or a PD-L1 positive advanced relapsed or ...
The purpose of this study is to test the safety, tolerability and anti-tumor activity of the research study drug, pembrolizumab ...
Exact
Phase N/A
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A Phase III Randomized Trial for Newly Diagnosed High Risk B-Lymphoblastic Leukemia (B-ALL) Including a Stratum Evaluating Dasatinib (NSC#732517 ...
This randomized phase III trial is studying how well combination chemotherapy works in treating young patients with newly diagnosed acute ...
Exact
Phase N/A
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A Phase 2 Study of the JAK1/JAK2 Inhibitor Ruxolitinib With Chemotherapy in Children With De Novo High-Risk CRLF2-Rearranged and ...
The purpose of this study is to find the best dose of ruxolitinib to use with standard chemotherapy in children ...
Exact
Phase N/A
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Multiple Phase 1 Safety Cohorts of Nivolumab Monotherapy or Nivolumab Combination Regimens Across Relapsed/Refractory Hematologic Malignancies
The purpose of this study is to test the effectiveness (how well the drug works), safety, and tolerability of an ...
Exact
Phase N/A
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