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Found 28 Carcinoma trials

A listing of Carcinoma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Study of Magrolimab Combination Therapy in Patients With Head and Neck Squamous Cell Carcinoma (ELEVATE HNSCC)

G
Greg Durm, MD
18-100 years
All genders
Phase 2
Interventional
What is this study about?The goals of this clinical study are to learn about the safety, tolerability, dosing andveness of the study drug, magrolimab in combination with other anticancer therapies inwith head and neck squamous cell carcinoma (HNSCC). THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most oncology …
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Molecular and Pathological Correlates of Treatment Outcome in Patients with Thymoma and Thymic Carcinoma

P
Patrick Loehrer, MD
1-100 years
All genders
What is this study about?The major purpose of this research study is to obtain blood samples from child and adult patients diagnosed with thymoma and/or tissue samples from patients undergoing surgery for their thymoma.  We will use these specimens to test for certain characteristics that we think will be useful …
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TheraSphere With Durvalumab and Tremelimumab for HCC (ROWAN)

P
Paul Haste
18-100 years
All genders
Phase 2
Interventional
The objective of the ROWAN clinical study is to assess the efficacy of local tumor control in HCC patients who receive TheraSphere followed by durvalumab and tremelimumab.
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APOLLO: A Randomized Phase II Double-Blind Study of Olaparib Versus Placebo Following Curative Intent Therapy in Patients With Resected Pancreatic Cancer and a Pathogenic BRCA1, BRCA2 or PALB2 Mutation

A
Anita Turk, MD
18-100 years
All genders
Phase 2
Interventional
This phase II trial investigates how well the addition of olaparib following completion ofurgery and chemotherapy works in treating patients with pancreatic cancer that has beenurgically removed (resected) and has a pathogenic mutation in BRCA1, BRCA2, or PALB2.b is an inhibitor of PARP, an enzyme that helps repair deoxyribonucleic acid …
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A Study to Assess the Effect of Y-90 Therapy on Non-target/Background Liver

M
Mark Tann, MD
18-100 years
All genders
The primary question of interest is quantifying the relationship between Y-90 liver therapy and liver damage.
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A Randomized Phase II Study of Anti-PD1 Antibody [MK-3475 (Pembrolizumab)] Alone Versus Anti-PD1 Antibody Plus Stereotactic Body Radiation Therapy in Advanced Merkel Cell Carcinoma

A
Ahmad Al-Hader, MD
18-100 years
All genders
This randomized phase II trial studies how well pembrolizumab with or without stereotactic body radiation therapy works in treating patients with merkel cell cancer that has spread to other places in the body.
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A Phase II Trial of Atezolizumab plus Chemotherapy after Progression on Single Agent PD-1 or PD-L1 Inhibitor in Cisplatin-ineligible Patients with Advanced Urothelial Carcinoma

N
Nabil Adra, MD
18-100 years
All genders
The purpose of this study is to compare any good and bad effects of using Atezolizumab along with the usual chemotherapy after progression with PD-1 or PD-L1 Inhibitor for individuals with urothelial carcinoma (cancer of the urinary tract).
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Pembrolizumab in MIBC

N
Nabil Adra, MD
18-100 years
All genders
Phase 2
Interventional
Subjects with cT2-T3N0M0 urothelial cancer of the bladder will be enrolled. After completingwo cycles of pembrolizumab, subjects will undergo a restaging MRI of the abdomen and pelvis with a standard acquisition protocol (as outlined in the protocol) as well as CT chest. A CThe abdomen and pelvis may be performed …
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A Pilot Study to assess Theragnostically Planned Liver Radiation with Functional DVH Analysis to Optimize Individualized Radiation Therapy

R
Ryan Rhome, MD
18-100 years
All genders
The purpose of this study is to compare radiation treatment plans that are designed for patients with liver cancer.
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Sentinel lymph node biopsy for cutaneous squamous cell carcinoma of the head and neck

J
Jessica Yesensky, MD
18-100 years
All genders
The purpose of this study is to research if a type of biopsy known as sentinel lymph node biopsy (SLNB) can help in determining the rate of tumor deposits that are hard to detect and identify in node-negative cutaneous squamous cell carcinoma of the head or neck. 
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