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Found 26 Infections trials

A listing of Infections medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Evaluation of Bacteria Types Associated with Ear Infections

S
Sarah Jo Mcdaniel Burgin
1-17 years
All genders
Observational
The purpose of this study is to understand the type of bacteria and viruses that grow in the middle ear. In the future, this could help ensure that the most appropriate antibiotic is prescribed for patients with ear infections. 

RDCRN PIDTC

M
Miriam Kim, DO
All genders
In this prospective and longitudinal natural history study, the aim is to identify variables that affect long-term outcomes following potentially life-saving Definitive Therapy (DT), which includes either 1) allogeneic hematopoietic cell transplant (HCT), or 2) autologous gene therapy (GT).

Utility of Serum Biomarkers in Diagnosing Fracture-Related Infections: A Pilot Study

R
Roman Natoli, MD
18-85 years
Healthy Volunteer
All genders
The primary aim will be to determine if serum inflammatory biomarkers can reliably diagnose FRIs as compared to a standardized definition of FRI.

Preventing cervical cancer in HIV-infected Kenyan and Ugandan women

21-60 years
Female
The first study goal is to evaluate HR-HPV DNA testing of self-collected vaginal swabs combined with VIA in screening for cervical cancer in HIV-infected women living in Kenya or Uganda.The second study goal is to determine if aflatoxin is a risk factor for cervical cancer among HIV-infected Kenyan and Ugandan …

se of Tecovirimat (TPOXX®) for Treatment of Human Non-Variola Orthopoxvirus Infections i

J
John Christenson, MD
All genders
The purpose of this expanded access IND (compassionate use) program is to provide stockpiled tecovirimat for treatment of non-variola orthopoxvirus infections and secondary treatment of complications from replication-competent vaccinia vaccine in adults and children.

Use of Tecovirimat (TPOXX®) for Treatment of Human Orthopoxvirus Infections.

E
Emily Marie Gould
All genders
EXPANDED ACCESS IND: The purpose of this expanded access IND treatment program is to provide tecovirimat for primary or early empiric treatment of confirmed or suspected (based on clinical signs and symptoms with known exposure while laboratory confirmation may be pending) non-variola orthopoxvirus infections (e.g., vaccinia, monkeypox, cowpox or other …

Influence of the vaginal microbiome on cervical cell metabolism during chlamydial infection

S
Stephen Jordan
18-35 years
Female
The purpose of this study is to understand if specific vaginal microbes (part of the microbiome), and their metabolites (that is, their byproducts) in women who have Bacterial Vaginosis (BV) and in women who do not have BV increase the risk for being infected with chlamydia. Information that we learn …

A Prospective and Retrospective Observational Study of Multidrug-Resistant Patient Outcomes With and Without Ibalizumab (PROMISE-US)

K
Kassem Bourgi, MD
18-100 years
All genders
Observational
The virological efficacy of ibalizumab has been clearly demonstrated in multiple clinical trials. This study will expand ibalizumab's clinical data set and allow a better understanding of the virologic response durability on ARV regimens with or without ibalizumab in a heterogeneous real-world patient population. Additional data on the efficacy and …

Virus Specific Cytotoxic T-Lymphocytes (CTLs) for Refractory Cytomegalovirus (CMV)

S
Scott Goebel, MD
1-30 years
All genders
Phase 2
Interventional
CMV cytotoxic T cells (CTLs) manufactured with the Miltenyi CliniMACS Prodigy Cytokine Capture System will be administered in children, adolescents and young adults (CAYA) with refractory cytomegalovirus (CMV) infection post Allogeneic Hematopoietic Stem Cell Transplantation (AlloHSCT), with primary immunodeficiencies (PID) or post solid organ transplant. Funding Source: FDA OOPD

EBV-specific Cytotoxic T-lymphocytes (CTLs) for Refractory EBV Infection

S
Scott Goebel, MD
1-30 years
All genders
Phase 2
Interventional
Related donor Epstein-Barr Virus (EBV) specific cytotoxic T cells (CTLs) manufactured with the Miltenyi CliniMACS Prodigy Cytokine Capture System will be administered in children, adolescents and young adults with refractory EBV infection post Allogeneic Hematopoietic Stem Cell Transplantation (AlloHSCT), with primary immunodeficiencies (PID) or post solid organ transplant. Funding Source: …
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