-
PHO-COG-CROOP-ADVL1312; A Phase 1/2 Study of AZD1775 (MK-1775) in Combination With Oral Irinotecan in Children Adolescents and Young Adults ...
This phase I/II trial studies the side effects and best dose of WEE1 inhibitor MK-1775 and irinotecan hydrochloride in ...
Exact
Phase N/A
-
A Phase 1/2 Study of Nivolumab in Children Adolescents and Young Adults With Recurrent or Refractory Solid Tumors as ...
The purpose of this study is to determine the side effects and best dose of nivolumab when given with or ...
Exact
Phase N/A
-
A Phase 1 Study of Selinexor (KPT-330 IND#125052) a Selective XPO1 Inhibitor in Recurrent and Refractory Pediatric Solid Tumors ...
The investigators will conduct a phase 1 trial of Selinexor in children with recurrent or refractory solid tumors, including CNS ...
Exact
Phase N/A
-
A Phase 1 Study Of Ramucirumab a Human Monoclonal Antibody Against the Vascular Endothelial Growth Factor-2 (VEGFR-2) Receptor in Children ...
The main purpose of this study is to evaluate the safety of the study drug known as ramucirumab in children ...
Exact
Phase N/A
-
A Phase 1 Multi-center Open-label Dose De-escalation Study to Evaluate the Safety and Efficacy of Talimogene Laherparepvec in Pediatric Subjects ...
This is a phase 1 study to evaluate the safety of intralesional talimogene laherparepvec administration in pediatric subjects with advanced ...
Exact
Phase N/A
-
A Phase 1 Study of Entinostat an Oral Histone Deacetylase Inhibitor in Pediatric Patients With Recurrent or Refractory Solid Tumors ...
This phase I trial studies the side effects and best dose of entinostat in treating pediatric patients with solid tumors ...
Exact
Phase N/A
-
A Phase 1 Study of ABI-009 (NAB-RAPAMYCIN) in Pediatric Patients With Recurrent or Refractory Solid Tumors Including CNS Tumors as ...
This phase I trial studies the side effects and best dose of nanoparticle albumin-bound rapamycin when given together with temozolomide ...Exact
Phase N/A
-
A Phase 1/2 Study of Lenvatinib in Combination With Everolimus in Recurrent and Refractory Pediatric Solid Tumors Including CNS ...
In this study, you will receive the combination of lenvatinib with everolimus. The main purpose of this study is: To ...Exact
Phase N/A
-
A Phase 1 Study of Pevonedistat (MLN4924) a Cullin Ligase Inhibitor in Combination With Temozolomide and Irinotecan in Pediatric Patients ...
This phase I trial studies the side effects and best dose of pevonedistat when giving together with irinotecan hydrochloride and ...Exact
Phase N/A
-
A Phase 1/2 Trial of VX15/2503 in Children Adolescents or Young Adults With Recurrent or Relapsed Solid Tumors
This phase I/II trial studies the side effects and best dose of anti-SEMA4D monoclonal antibody VX15/2503 (VX15/2503 ...Exact
Phase N/A
Showing - of studies