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Found 8 Radiotherapy trials

A listing of Radiotherapy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Testing the Addition of Chemotherapy Drug, Cisplatin, to Usual Radiation Therapy for Patients with Head and Neck Cancer

G
Greg Durm, MD
18-100 years
All genders
Phase 2
Interventional
The purpose of this study is to compare two treatment approaches that are currently used after surgery for head and neck cancer. One approach is to administer radiation therapy alone. A second approach is to administer radiation therapy along with the chemotherapy drug, cisplatin.
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Biomarkers of endothelial dysfunction in pediatric patients receiving high intensity chemotherapy/irradiation

J
Jodi Skiles
All genders
The purpose of this study is to collect blood specimens and data from patients undergoing stem cell transplant.
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A Pilot Study to assess Theragnostically Planned Liver Radiation with Functional DVH Analysis to Optimize Individualized Radiation Therapy

R
Ryan Rhome, MD
18-100 years
All genders
The purpose of this study is to compare radiation treatment plans that are designed for patients with liver cancer.
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Randomized Phase II/III Trial of Radiotherapy with Concurrent MEDI4736 (Durvalumab) vs. Radiotherapy with Concurrent Cetuximab in Patients with Stage III-IVB Head and Neck Cancer with a Contraindication to Cisplatin

G
Greg Durm, MD
18-100 years
All genders
The purpose of this study is to compare any good and bad effects of usual radiation plus the study treatment, MEDI4736 (durvalumab), to the usual therapy of radiation plus cetuximab in patients with head and neck cancer who cannot take the drug cisplatin.
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Post-Surgical Stereotactic Radiotherapy (SRT) Versus GammaTile-ROADS (Radiation One and Done Study)

A
Angela M. Richardson, MD, PhD
18-100 years
All genders
Phase 3
Interventional
This trial will be a randomized controlled study comparing the efficacy and safety ofve radiation therapy using GammaTilesTM (GT) versus SRS 3-4 weeks followingumor resection which is the current standard of care.
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ONC201 in H3 K27M-mutant Diffuse Glioma Following Radiotherapy (the ACTION Study) (ACTION)

All genders
Phase 3
Interventional
This is a randomized, double-blind, placebo-controlled, parallel-group, international, Phase 3 study in patients with newly diagnosed H3 K27M-mutant diffuse glioma to assess whetherwith ONC201 following frontline radiotherapy will extend overall survival andgression-free survival in this population. Eligible participants will have histologically diagnosed H3 K27M-mutant diffuse glioma and have completed standard …
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A Phase 3 Randomized, Placebo-Controlled Trial Evaluating Memantine (IND# 149832) for Neurocognitive Protection in Children Undergoing Cranial Radiotherapy as Part of Treatment for Primary Central Nervous System Tumors

S
Sandeep Batra, MD
4-18 years
All genders
Phase 3
Interventional
To determine the efficacy, as measured by the slope of change of the Cogstate composite Z score from baseline to 12 months, of oral memantine administered for a period of 6 months, when compared to placebo, in children ages 4-18 receiving cranial or craniospinal radiotherapy for primary central nervous system …
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TAILOR RT: A Randomized Trial of Regional Radiotherapy in Biomarker Low Risk Node Positive Breast Cancer

R
Richard Zellars, MD
40-100 years
Female
The purpose of this study is to compare the effects on low risk breast cancer receiving usual care that includes regional radiation therapy, with receiving no regional radiation therapy.
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