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Found 16 Lung Disease trials

A listing of Lung Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Temozolomide and Atezolizumab as Second or Third Line for the Treatment of Metastatic or Recurrent Small Cell Lung Cancer

G
Greg Durm, MD
18 years and older
All genders
Phase 2
Interventional
This phase II trial studies the effects of temozolomide and atezolizumab as second or thirdwith small cell lung cancer that has spread to other places inhe body (metastatic) or has come back (recurrent). Chemotherapy drugs, such as temozolomide, work in different ways to stop the growth of tumor cells, either …
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Long Term Follow up of the Lung Transplant Outcomes Group Cohort

M
Mrunal Patel
100 years and younger
All genders
Define long-term CLAD phenotype of lung transplant recipients whoparticipated in LTOG cohort studies Determine the long-term functional status and well-being of lungtransplant recipients who participated in LTOG cohort studies
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A randomized phase II trial of adjuvant Pembrolizumab versus observation following curative resection for stage I non-small cell lung cancer (NSCLC) with primary tumors between 1-4 cm

G
Greg Durm, MD
18-100 years
All genders
Phase 2
Interventional
This is a research study to find out if giving a drug called pembrolizumab after lung cancer surgery does a better job at keeping the cancer from coming back than surgery alone.
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Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

S
Shadia Jalal, MD
18 years and older
All genders
Phase 2/3
Interventional
This screening and multi-sub-study randomized phase II/III trial will establish a method for genomic screening of similar large cancer populations followed by assigning and accruingultaneously to a multi-sub-study hybrid Master Protocol (Lung-MAP). The type of cancer(biomarker) will determine to which sub-study, within this protocol, a participant will be assigned to …
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A Phase 1a/1b Study of an Anti-IDO-1 Agent (LY3381916) Administered Alone or in Combination with Anti-PD-L1 Checkpoint Antibody (LY3300054) in Solid Tumors

S
Shadia Jalal, MD
18-100 years
All genders
The purpose of this study is to evaluate the safety of the study drug LY3381916 administered alone or in combination with anti-programmed cell death ligand 1 (PD-L1) checkpoint antibody (LY3300054).
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Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma

S
Sandeep Batra, MD
50 years and younger
All genders
Phase 3
Interventional
This phase III trial compares the effect of open thoracic surgery (thoracotomy) tohoracoscopic surgery (video-assisted thoracoscopic surgery or VATS) in treating patients with osteosarcoma that has spread to the lung (pulmonary metastases). Open thoracic surgeryype of surgery done through a single larger incision (like a large cut) that goes between …
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