Found 25 Liver Disease trials
A listing of Liver Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Phase 2b Study of GSK4532990 in Adults With NASH (HORIZON)
N
Niharika Samala, MD
Phase 2
The purpose of this study is to measure improvements in liver fibrosis and inflammation with GSK4532990 compared with placebo in participants with NASH and advanced (F3) fibrosis. Theudy duration will be up to 76 weeks including the screening period. The treatment duration will be up to 52 weeks.
Genetic Collection Protocol
J
Jean Molleston, MD
This study involves the one-time collection of whole blood or saliva samples for thed storage of DNA for use in ongoing and future ChiLDReN studies.
Nonalcoholic Fatty Liver Disease (NAFLD) Pediatric Database 2
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Jean Molleston, MD
The purpose of the NAFLD Pediatric Database 2 is to better understand nonalcoholic fatty liver disease (''NAFLD) by following and evaluating children with this condition yearly.
Vitamin E Dosing Study (VEDS)
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Naga Chalasani, MD
Phase 2
This is a multicenter, randomized, double masked, placebo-controlled, parallel treatment groups dosing trial of Vitamin E in adult nonalcoholic fatty liver disease (NAFLD).
Biospecimens of Patients with Cholestatic Liver Disease
C
Craig Lammert, MD
The purpose of this study is to create a resource of biospecimens (bodily fluids/samples) from people with Primary Sclerosing Cholangitis (PSC) and to use these samples for current and future research relating to PSC.
Longitudinal Study of Mitochondrial Hepatopathies (MITOHEP)
J
Jean Molleston, MD
The specific aims of this study are (1) to determine the clinical phenotypes and natural history of hepatic RC and FAO disorders, (2) to determine the correlation between genotyped phenotype, (3) to determine if circulating biomarkers reflect diagnosis and predict liver disease progression and survival with the native liver, (4) …
Longitudinal Study of Genetic Causes of Intrahepatic Cholestasis (LOGIC) (LOGIC)
J
Jean Molleston, MD
Cholestasis is a condition in which bile is not properly transported from the liver to the. Cholestasis can be caused by an array of childhood diseases, including the genetic diseases Alagille syndrome (ALGS), alpha-1 antitrypsin (a-1AT) deficiency, bile acidynthesis and metabolism defects, and progressive familial intrahepatic cholestasis (PFIC) or benign …
Idiosyncratic Liver Injury Associated with Drugs (ILIAD): A Retrospective Study
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Naga Chalasani, MD
This study is examining why some individuals develop liver reactions to certain types of medications.
A 5-Year Longitudinal Observational Study of Patients with Nonalcoholic Fatty Liver or Nonalcoholic Steatohepitiis
Niharika Samala, MD
The purpose of this study is to create a research registry of patients with NAFL (non alcoholic fatty liver) or NASH (non alcoholic steatohepatitis)in order to assess the safety and effectiveness of current and future therapies. The goal is to identify the factors associated with favorable versus suboptimal clinical response …
TReatment for ImmUne Mediated PathopHysiology (TRIUMPH)
J
Jean Molleston, MD
Phase 2
TReatment for ImmUne Mediated PathopHysiology (TRIUMPH) is a multi-center, three arm,domized, controlled trial of immunosuppressive therapy for children with acute liverure. The study will determine if suppressing inflammatory responses with eitherds or equine anti-thymocyte globulin therapy improves survival for children withhis rare, life-threatening condition.
