Binge & High-Intensity Drinking
M
Martin Plawecki, MD, PhD
Primary Investigator
Overview
The purpose of this study is to examine the relationships between drinking behaviors in both normal life and in our laboratory. Results from this study may help us better understand the relationships between drinking behavior, family drinking history and brain function.
Description
Participants will complete a screening visit (unless it was already completed as part of another related study), two (2) alcohol infusion sessions over 1-2 weeks, followed by an Functional Magnetic Resonance Imaging (fMRI) session a week or two later.
Eligibility
You may be eligible for this study if you meet the following criteria:
-
Conditions:
Binge drinking, alcoholism
-
Age: Between 21 Years - 35 Years
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Gender: All
Inclusion Criteria:
- Overtly healthy men and women aged 21 – 35
- At least 3 or 4 drinks on an occasion for women and men, respectively over the last month, unless determined by PI that drinking history meets study objectives
- Right-handed
Exclusion Criteria:
- MRI Contraindications
- Pregnant or breast-feeding women
- Desire for AUD treatment or court ordered to not drink alcohol
- Medical or non-AUD psychiatric disorders, such as seizure disorder, schizophrenia, or other conditions that may influence study outcome or participant safety
- Positive urine drug screen for amphetamines/ methamphetamines, barbiturates, benzodiazepines, cocaine, opiates, or phencyclidine and/or evidence of intoxication
- Medications or dosage changes (past 30 days) that could influence data/participant safety (e.g., antidepressants, antipsychotics, benzodiazepines, etc.) as determined by PIs
- Current/history of neurological disease of cerebral origin, head injury with > 20 min loss of consciousness, or medical treatment impacting MRI data integrity or representativeness
- Positive BrAC reading precluding visit completion
- Actively suicidal (any suicide attempts within the past year or any current suicidal intent, including a plan) or are at serious suicidal risk, by clinical evaluation by the PIs
- Left-handed or ambidextrous
- Inability to understand and comply with study instructions in English
- Any reason for which the PI determines that inclusion in the study would compromise the safety of the subject or integrity of the study.
Updated on
03 May 2024.
Study ID: 17502, PSYC-IIR-DRTS
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