A listing of Fracture medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
The purpose of this study is to assess the effects of skeletal trauma on the human metabolome, or the pathways by which the body creates, stores, and breaks down energy.
The overall aim of this proposal is to identify a biomarker diagnostic strategy that can be implemented in patients sustaining fractures at high-risk for infection. This proposal will address the hypothesis that there is a biomarker signature that will be able to discriminate between patients who develop FRI compared to …
The purpose of this study is to investigate the role of Next Generation Sequencing (NGS), a molecular method to detect bacterial DNA presence, in 1) diagnosis of infected nonunion compared to microbiological culture and 2) compare NGS signal with clinical outcome and fracture healing.
This study will examine whether the stiffness of a partially healed bone, measured using a 3D image and computer simulation constructed from a CT scan can predict at a very early stage if there are problems with how the bone is healing.
The purpose of this study is to determine if certain molecules in the bloodstream can be used to improve our ability to predict the development of a nonunion or unhealed bone or fracture related infection. This study is looking at many molecules and we will determine if the levels of …
The purpose of this study is to compare clinical outcomes of patients that underwent IMN for tibial plateau fractures to patients that underwent ORIF for similar fractures; and to compare clinical outcomes of patients that underwent IMN for tibial pilon fractures to patients that underwent ORIF for similar fractures.
The proposed study is a two arm, pragmatic, randomized controlled multicenter Phase IIIy trial. 1,000 patients with tibia fractures treated with intramedullary (IM)will be randomized into two treatment arms. The control arm will receive standard paingement and no NSAIDs. The treatment arm will receive standard pain management plus up toweeks …
To define a serum protein-based diagnostic for the progression and failure of fracture healing, through the identification of a set of serum proteins that appear at early times of biological healing and show a specific correlation with later radiological and functional signs used to define delayed healing and non-union.