A listing of roman-natoli-md medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
The overall aim of this proposal is to identify a biomarker diagnostic strategy that can be implemented in patients sustaining fractures at high-risk for infection. This proposal will address the hypothesis that there is a biomarker signature that will be able to discriminate between patients who develop FRI compared to …
The purpose of this study is to investigate the role of Next Generation Sequencing (NGS), a molecular method to detect bacterial DNA presence, in 1) diagnosis of infected nonunion compared to microbiological culture and 2) compare NGS signal with clinical outcome and fracture healing.
The purpose of this study is to help determine the best treatment for preventing blood clots that are formed following trauma that could potentially lead to death.
This study will examine whether the stiffness of a partially healed bone, measured using a 3D image and computer simulation constructed from a CT scan can predict at a very early stage if there are problems with how the bone is healing.
To define a serum protein-based diagnostic for the progression and failure of fracture healing, through the identification of a set of serum proteins that appear at early times of biological healing and show a specific correlation with later radiological and functional signs used to define delayed healing and non-union.
The purpose of this study is to determine if certain molecules in the bloodstream can be used to improve our ability to predict the development of a nonunion or unhealed bone or fracture related infection. This study is looking at many molecules and we will determine if the levels of …
The COgnitive and Physical Exercise to improve Outcomes after Surgery (COPE-iOS) study isg the hypothesis that a pragmatic program combining computerized cognitive training andhysical training throughout the perioperative period will improve long-term cognitive and disability outcomes in older surgical patients at high risk for decline. To accomplish these goals, the …
Approximately 1000 patients presenting with tibial shaft fractures (AO type 42) will bed prospectively in this registry. All patients are treated and followed at 6 weeks, 6hs and 1 year postoperative always following the local standard of care (routine) visithedule up to 36 months if required. Data collection includes patient …
The purpose of this study is to compare the usual practice of bearing weight (“delayed weight bearing”) with weight bearing sooner in the healing process. We will use study data to determine if early weight bearing improves recovery after injury.